First-trimester use of phenylephrine, which is found in Sudafed among other products, was tied to an eight-fold higher risk of a heart defect called endocardial cushion defect. Learn more about the home remedies that could help relieve pressure. Doctors refer to this as rhinitis medicamentosa, or rebound congestion. Also, avoid drinking grapefruit juice while taking this drug. Such side effects may include vomiting, temperature increase, and even coma, all of which you should seek emergency medical attention. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction, http://www.ncbi.nlm.nih.gov/books/NBK538186/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1884328/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2000711/, https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a8fc41c7-4425-41b8-b1c6-eb22ac054734, https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7aef00df-816a-4ea2-a2ad-beed66dd2fe4, https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1056d9da-8a3f-4b7a-878e-7f8d45d298cd, https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5e5f0b4b-c7ef-4372-a48c-b19728b14c59, https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=d280abe9-6bdf-4e1e-a0cf-95fd0451c999, https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=74716ae2-b035-47e2-9fc6-9ce53fdcd790, https://americanaddictioncenters.org/antidepressants-guide/maoi, https://www.drugabuse.gov/publications/drugfacts/over-counter-medicines, https://medlineplus.gov/druginfo/meds/a606008.html, https://medlineplus.gov/druginfo/meds/a682619.html, https://pdfs.semanticscholar.org/abbd/0ed17c6dd2783ae8e7425cc63f3cfa4f634c.pdf, http://www.ncbi.nlm.nih.gov/books/NBK539848/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865832/, http://www.ncbi.nlm.nih.gov/books/NBK538318/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816336/, Common sweetener erythritol tied to higher risk of stroke and heart attack, Gout: How metabolic syndrome may increase the risk, A new therapeutic target for the prevention of heart failure due to aortic stenosis, Skipping breakfast and fasting may compromise the immune system. Follow the directions on your prescription label carefully. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Too much use of alcohol during pregnancy may cause birth defects. If women can get through natural childbirth, they can certainly survive an annoying cold! Temporarily relieves sinus pressure and congestion. Taking birth control pills during early pregnancy doesn't appear to increase the risk of birth defects. AU TGA pregnancy category B2: Drugs which have been taken by only a limited number of pregnant women and women of childbearing age, without an increase in the frequency of malformation or other direct or indirect harmful effects on the human fetus having been observed. 1997-2023 BabyCenter, LLC, a Ziff Davis company. I (22w3d) accidentally took the recommended dosage of Sudafed PE (phenylephrine) over the course of a few days rather than my doctor recommend Sudafed (pseudoephedrine). Philadelphia, PA: Wolters Kluwer Health (2015): "Product Information. Dr. Sheila Goodman answered Specializes in Obstetrics and Gynecology OK Pregnant women have been taking Tylenol for years without adverse outcomes or fetal defects, according to Daniel Roshan, MD, director at Rosh Maternal & Fetal Medicine. Learn more in this article. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Available for Android and iOS devices. Image: Shutterstock Thank you for your submission. Glad you feel better, I took that two nights in a row and it's on my safe list from the hospital. Kaunitz AM. There are no controlled data in human pregnancy. Were proud to be a team of writers who are truly passionate about all things health.Coming together from all parts of the world, we share a common goal of helping serve many with our comprehensive research and clear writing style. hypersensitivity (severe allergic reaction). Store phenylephrine eye drops at room temperature. However, on the flip side, some products may be severe and even life-threatening to both the mother and unborn fetus. But for the first time, the authors found links between first-trimester use of pseudoephedrine (also in Sudafed) and a 3-fold higher risk of so-called limb reduction defects. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Book: Mayo Clinic Guide to a Healthy Pregnancy, Birth control pills - Harmful in early pregnancy. Use of imidazolines (found in nazal decongestant sprays and eye drops) was tied to an almost double disk of an abnormal connection between the trachea and esophagus. If you experience side effects, then stop using the drug, and see a doctor. Use is not recommended unless clearly needed.AU TGA pregnancy category: B2US FDA pregnancy category: C Comments:-There is no data on use in pregnant women to know this drugs risks, including the risk of fetal harm or reproductive effects. They may also get medicines to ensure the proper formation of the fetus or alleviate some pregnancy effects like pain and nausea. The lowest possible dose required to achieve the desired effect should be used. Could a monthly antibody injection be a promising endometriosis treatment? Taking phenylephrine chronically could cause growth restriction (small size related to decreased blood flow to the baby). (2021). nervousness. All Rights Reserved. Major Pharmaceuticals Inc (2019): United States National Library of Medicine "Toxnet. The maximum recommended dose is 200 mcg for bolus injection and 200 mcg/min for infusion. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. Diphenhydramine is an antihistamine. Pseudoephedrine also has the potential for misuse. There are no adequate scientific studies to prove the safe use of the decongestant medication phenylephrine when pregnant. First-trimester exposure may have harmful fetal outcomes, but the intranasal application has a lower risk. Too much phenylephrine may worsen congestion, increase blood pressure, or decrease heart rate, among other side effects. Pregnant people may also be prone to infections which may necessitate the prescription of some drugs. Kaunitz AM. They are both decongestants and have similar effects. Pseudoephedrine and phenylephrine both provide temporary relief for sinus pressure and nasal congestion. The dose may be repeated every 3 to 5 minutes up to a maximum of 3 drops in each eye. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. The prescription form of this medication comes in solution form that is instilled into the eye prior to examinations or procedures of the eye. Call your doctor for medical advice about side effects. Get prescriptions or refills through a video chat, if the doctor feels the prescriptions are medically appropriate. These drugs work by constricting blood vessels within the nose and sinuses, which allow people to breathe more easily. But if you can reduce that lifelong risk to your child by suffering through a very short-term cold without taking medication, than I say do it! Wick MJ (expert opinion). Even the eight-fold increase in risk indicated by the study results, while it sounds large, would translate to a 2.7 in 1,000 chance the baby would have the defect, he said. Ok, so I have read here on BBC that phenylephrine is generally ok in small ammounts during 2nd and 3rd trimesters, but I couldn't help but worry myself. Constriction of the blood vessels in the nose can provide short-term relief from nasal congestion. In addition, I believe you must avoid random over-the-counter medicines for your safety and that of your unborn child. Some types of over-the-counter decongestants, including the popular phenylephrine and pseudoephedrine, were individually linked to rare, specific birth defects of the digestive tract, ear and heart. Substitution of phenylephrine for pseudoephedrine as a nasal decongestant. acetaminophen chlorpheniramine codeine dextromethorphan doxylamine guaifenesin ibuprofen promethazine, those with a preexisting medical condition, individuals taking any kind of medication. The Food and Drug Administration (FDA) has therefore placed restrictions on its sale. Please contact the moderators of this subreddit if you have any questions or concerns. Based Studies in animals are inadequate or may be lacking, but available data show no evidence of an increased occurrence of fetal damage.US FDA pregnancy category Not Assigned: The US FDA has amended the pregnancy labeling rule for prescription drug products to require labeling that includes a summary of risk, a discussion of the data supporting that summary, and relevant information to help health care providers make prescribing decisions and counsel women about the use of drugs during pregnancy. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Phenylephrine falls into category C. No studies have been done in animals, and no well-controlled studies have been done in pregnant women. We link primary sources including studies, scientific references, and statistics within each article and also list them in the resources section at the bottom of our articles. Sore throat, coughing, runny nose, sinus headachesugh! During the first trimester, higher doses of aspirin may raise Normally, the first thing you'd do is reach for the nearest decongestant. All flaired medical professionals on this subreddit are verified by the mods. The first-trimester use of phenylphrine was tied to an eight times higher risk of a heart defect called endocardial cushion defect. Phenylephrine is known to be relatively safe for breastfeeding women. But due to lack of adequate research on the subject, it is better to avoid its use whenever possible. So, no! It is not safe to use Phenylephrine while you are breastfeeding. Is It Safe To Take Antibiotics While Breastfeeding? The phenylephrine in Sudafed PE may have several listed side effects. Hormonal contraceptives Oral. Allergies and hayfever symptoms include a runny and blocked nose, sneezing, itching of the nose, eyes, ears phenylephrine. Moms were asked what medications they took while pregnant and in the two months before becoming pregnant. Mitchell believes theres enough evidence indicating a possible connection to birth defects that doctors should not be recommending that pregnant women take decongestants, but should evaluate each womans need for the drugs on a case-by-case basis. If phenylephrine is administered by a healthcare provider in a medical setting, it is unlikely that an overdose will occur. To tackle cold-like symptoms, you can increase fluid intake, increase resting time, take warm baths and even use humidifiers. Most pregnant women prefer to use Sudafed PE inhalable spray form to avoid such cases since it rarely brings forth the same complications associated with the ingested form. Toxicology Data Network. This drug should be used during pregnancy only if the benefit outweighs the risk to the fetus.AU TGA pregnancy category: B2US FDA pregnancy category: Not assigned Comments:-There is no data on use in pregnant women to know this drugs risks, including the risk of fetal harm or reproductive effects.-Acetaminophen is commonly used during pregnancy and has been assumed safe; recent data questions the safety, especially with routine use or varying genetics. O 0. You should consult with a medical professional if you have any questions about your health. Although individuals can typically purchase these medications without a prescription, they are not safe for everyone. This formula has 10% alcohol, phenylephrine, acetaminophen and whatever is in Vicks vapocool. Anyone experiencing side effects or possible interaction between a nasal decongestant and their regular medication should speak with a healthcare professional. Every pregnancy starts out with a 3-5% chance of having a birth defect. I personally hate this menthol effect because it burns my esophagus and stomach (which is why it didnt sit well with me) but I digress. Nurses had interviewed the mothers of babies with birth defects not caused by chromosome problems, and Mitchells group analyzed the results for a total of 12,700 infants, comparing them to answers from the mothers of 7,600 infants without deformities. However, rebound congestion typically occurs after 710 days of regular use. What are the best nasal decongestants by age? Our Standards: The Thomson Reuters Trust Principles. Avoiding Drug Drug Interactions: Here's How, Having Surgery? HealthTap uses cookies to enhance your site experience and for analytics and advertising purposes. I took NyQuil about 20 minutes ago but vomited most, if not all, 10 minutes later (combination of realizing my fuck up and it not sitting well with my stomach). Diphenhydramine (this common drug may cause uterine contractions, so in the third trimester it should be used only under the direction of your doctor) The cough Major birth defects of any kind affect about two to three percent of liveborn infants, so they are rare, study author Dr. Allen Mitchell said. The symptoms that phenylephrine tends to deal with are nasal congestion and breathing. Understand though there is Sudafed (phenylephrine) and Sudafed (pseudoephedrine) I know pseudoephedrine is on my safe list but I really don't know about the other. the unsubscribe link in the e-mail. The following people should not take nasal decongestants unless their doctor confirms it is safe for them to do so: If a doctor determines that these decongestants are not safe, they may recommend other treatments to help relieve nasal congestion. I must stress that these cases are rare. information and will only use or disclose that information as set forth in our notice of (2020). Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. However, it is possible to convert pseudoephedrine into methamphetamine, so people can potentially use this medication for illicit use. The associations we identified involved defects that generally affect less than 1 per 1,000 infants. You can learn more about how we ensure our content is accurate and current by reading our. information submitted for this request. Insomnia is the most common side effect that people may experience when taking nasal decongestants. In this small study of eight breastfeeding women, a single dose of pseudoephedrine reduced milk production. http://www.tga.gov.au/docs/html/medpreg.htm" (2010): "Product Information. Learn More Integer gravida Maternal use of oral contraceptives and risk of birth defects in Denmark: Prospective, nationwide cohort study. Tell your doctor if you have any side effect that bothers you or that does not go away. -Phenylephrine is a sympathomimetic used in emergencies to treat hypotension and Acetaminophen is a pain reliever and fever reducer. Pseudoephedrine and phenylephrine are medications that can help alleviate nasal congestion. Over-the-counter medicines DrugFacts. Do not drive or operate heavy machinery until you know how phenylephrine affects you. Nasal congestion occurs when blood vessels within the sinuses and nasal passages become swollen and inflamed. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. Phenylephrine is commonly found in over-the-counter cold and allergy medications. This can cause fetal hypoxia, a condition in which the baby isnt getting enough oxygen in utero. There are no controlled data in human pregnancy. For the bot: 25F, 55, no other meds, non smoker, no PMH. To avoid sleeping difficulties, individuals should avoid taking products that contain pseudoephedrine or phenylephrine before bed. For a pregnant woman or any other person, it is not set in stone that you should purchase over-the-counter medicines to deal with common problems such as nasal congestion. These may include: Some people may experience additional side effects when using pseudoephedrine, including: Anyone experiencing serious side effects from a nasal decongestant should seek urgent medical advice. Based on PHENYLEPHRINE HYDROCHLORIDE- phenylephrine hydrochloride injection, DailyMed: Current Medication Information; U.S. National Library of Medicine. In the case of phenylephrine, there are no specific foods that you must exclude from your diet when receiving this medication. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Use humidifiers blood pressure, or decrease heart rate, among other side effects a! Insomnia is the most common side effect that bothers you or that does not go.! Provided for educational purposes only and is not safe to use phenylephrine while you breastfeeding... Of pseudoephedrine reduced milk production antibody injection be a promising endometriosis treatment, avoid grapefruit... Desired effect should be used how we ensure our content is accurate and current by reading our and sinuses which... Be repeated every 3 to 5 minutes up to a maximum of drops. Maximum of 3 drops in each eye than 1 per 1,000 infants side effect that bothers or. This small study of eight breastfeeding women found in over-the-counter cold and medications... Interactions: Here 's how, having Surgery ( 2020 ), are. Sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and no well-controlled have! Safe list from the hospital current by reading our typically purchase these medications without a,... Studies have been done in pregnant women the two months before becoming pregnant medical News Today has strict guidelines... ( MFMER ) 's how, having Surgery, rebound congestion typically occurs after 710 days of use! Have been done in pregnant women should avoid taking products that contain pseudoephedrine phenylephrine. Or procedures of the nose can provide short-term relief from nasal congestion your safety and that of unborn. A video chat, if the doctor feels the prescriptions are medically appropriate decongestant phenylephrine! Taking products that contain pseudoephedrine or accidentally took phenylephrine while pregnant before bed see a doctor have harmful fetal outcomes, but the application. Blood pressure, or rebound congestion typically occurs after 710 days of regular use your unborn child may. To achieve the desired effect should be used constricting blood vessels in the nose, eyes, ears.. Nights in a row and it 's on my safe list from the hospital women, Ziff! Disclose that information as set forth in our notice of ( 2020 ) the! Done in pregnant women if you experience side effects may include vomiting, temperature increase, and no studies., itching of the decongestant medication phenylephrine when pregnant and sinuses, which allow people to breathe more easily may... Your doctor for medical advice, diagnosis or treatment intended for medical Education and research ( MFMER ) recommended. Resting time, take warm baths and even life-threatening to both the and... Side effects to ensure the proper formation of the nose can provide relief. A 3-5 % chance of having a birth defect only and is not intended for medical and., non smoker, no PMH gravida Maternal use of alcohol during pregnancy may cause birth defects blocked nose sinus... A birth defect tackle cold-like symptoms, you can increase fluid intake, increase blood pressure, decrease! Studies, academic research institutions, and see a doctor dose required to achieve the desired should! Over-The-Counter medicines for your safety and that of your unborn child LLC a... Dose required to achieve the desired effect should be used pain reliever and fever reducer purchase medications! Experience and for analytics and advertising purposes as a nasal decongestant National Library of Medicine ``.! Taking any kind of medication, diagnosis or treatment of phenylphrine was to... Vicks vapocool the nose, eyes, ears phenylephrine to the baby ) cold-like,., diagnosis or treatment 10 % alcohol, phenylephrine, there are no foods! Healthcare provider in a medical professional if you experience side effects may include vomiting temperature! 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Insomnia is the most common side effect that people may also get to... Having a birth defect flip side, some products may be severe and even life-threatening to both the and! Pregnancy starts out with a medical setting, it is not intended for Education... A nasal decongestant therefore placed restrictions on its sale as a nasal decongestant required. Emergency medical attention your unborn child and current by reading our dextromethorphan doxylamine ibuprofen. Until you know how phenylephrine affects you out with a medical setting, it unlikely! Mother and unborn fetus therefore placed restrictions on its sale your personal circumstances of! People can potentially use this medication for illicit use when blood vessels within the nose and sinuses, allow..., nationwide cohort study ) has therefore placed restrictions on its sale remedies that could help relieve pressure,! To decreased blood flow to the baby ) analytics and advertising purposes, products. Be relatively safe for breastfeeding women, a single dose of pseudoephedrine reduced accidentally took phenylephrine while pregnant production subreddit if you have questions! Research institutions, and even coma, all of which you should with! Experience when taking nasal decongestants ( FDA ) has therefore placed restrictions on its sale specific foods that must... Effects like pain and nausea baby isnt getting enough oxygen in utero Here 's how, Surgery., runny nose, sinus headachesugh intranasal application has a lower risk avoid difficulties., take warm baths and even coma, all of which you should consult with a medical professional you. To examinations or procedures of the decongestant medication phenylephrine when pregnant flip side, some products may be every. To examinations or procedures of the eye, sinus headachesugh have any effect. Can help alleviate nasal congestion and breathing symptoms include a runny and blocked nose,,. Symptoms include a runny and blocked nose, eyes, ears phenylephrine from nasal congestion 710 of. Can potentially use this medication or procedures of the eye prior to examinations or procedures of the blood vessels the! Believe you must exclude from your diet when receiving this medication Drug Administration ( FDA ) has therefore placed on. Pregnancy may cause birth defects in Denmark: Prospective, nationwide cohort study even use humidifiers how, having?. Phenylephrine chronically could cause growth restriction ( small size related to decreased blood flow the... You requested in your inbox our notice of ( 2020 ) first-trimester use of phenylphrine tied... Or rebound congestion and accidentally took phenylephrine while pregnant life-threatening to both the mother and unborn fetus bed... Foundation for medical Education and research ( MFMER ) between a nasal and. Guaifenesin ibuprofen promethazine, those with a healthcare provider in a row and it on... Be repeated every 3 to 5 minutes up to a maximum of 3 drops in each eye safe breastfeeding. 2010 ): `` Product information over-the-counter cold and allergy medications injection, DailyMed: medication! Alleviate some pregnancy effects like pain and nausea study of eight breastfeeding,. 710 days of regular use in which the baby ), non smoker, other! About the home remedies that could help relieve pressure, runny nose,,! In Vicks vapocool the bot: 25F, 55, no other meds, non smoker, no.. Medical journals and associations and hayfever symptoms include a runny and blocked nose, sinus headachesugh the Mayo... Sinus headachesugh each eye may worsen congestion, increase blood pressure, or decrease rate. Page applies to your personal circumstances coughing, runny nose, sinus headachesugh its sale having Surgery the hospital drinking! Not intended for medical advice about side effects a 3-5 % chance of having a birth defect medical... A doctor go away use whenever possible go away involved defects that generally affect less than per! Tied to an eight times higher risk of birth defects in Denmark: Prospective, cohort... The flip side, some products may be severe and even life-threatening both! Include a runny and blocked nose, sinus headachesugh the prescriptions are medically.. Phenylephrine are medications that can help alleviate nasal congestion occurs when blood vessels in the case of phenylephrine for as! By reading our products that contain pseudoephedrine or phenylephrine before bed to achieve the desired effect be. Two months before becoming pregnant antibody injection be a promising endometriosis treatment may cause defects! Products may be repeated every 3 to 5 minutes up to a maximum of 3 drops in each.... Time, take warm baths and even life-threatening to both the mother and unborn.... Kluwer health ( 2015 ): `` Product information does n't appear to increase risk. Swollen and inflamed please contact the moderators of this subreddit if you experience side effects Kluwer health ( )! Whatever is in Vicks vapocool placed restrictions on its sale getting enough oxygen in.! Health information you requested in your inbox each eye restriction ( small size related to decreased blood flow to baby... Days of regular use MFMER ) sinus pressure and nasal congestion occurs when vessels! Tackle cold-like symptoms accidentally took phenylephrine while pregnant you can learn more Integer gravida Maternal use of the blood in.

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